Every drug has side effects, with many being particularly damaging to the liver. Liver damage is often visible on the skin showing up as either a single liver spot, or two or more symmetrical spots on both sides of the face (melasma).

For a list of liver-damaging sources and medications, see below.

Melasma Medications/Toxins

Alendronate Sodium Alprazolam
Buproprion
Chlordiazepoxide
Citalopram
Clonazepam
Conjugated Estrogen
Diazepam
Drospirenome
Elevated Pregnancy Hormones
Escitalopram
Estriol Sulfate
Estrodiol
Estrone
Estropipate
Ethynodiol Acetate
Equilin Sulfate
Hepatitis
Levonorgestrel
Lorazepam
Noregestimate
Norethindrone Acetate
Setraline
Testosterone

Liver Spot Medications/Toxins

Acetaminophen
Equilin sulfate
Oxidized Nickel
PFOA