






Winner of the 2023 Dermascope Aestheticians' Choice Awards for Favorite Retinol Serum
Calm Gentle Retinal Serum is the ultimate soothing serum carefully crafted for sensitive skin. This sun-safe, anti-aging formula gently brings your skin to life with liposomal-delivered collagen targeting ingredients and antioxidants. Essential nutrients restore a youthful complexion without irritation, making it gentle enough for sensitive skin. Embrace the barrier-supporting nutrients and let your skin flourish with renewed radiance and tranquility.
THIS PRODUCT:
- Gentle cell renewal with barrier protection
- Increases nutrient supply and moisture
Pay with FSA & HSA.
Here’s how to use your HSA/FSA funds.
Checkout as guest
Select Gale at Checkout
Complete a health assessment
Pay with HSA/FSA or credit card
Pay with credit or debit card
Subscribe with your regular debit or credit card – do not pay with an HSA/FSA card.
Connect your HSA/FSA
After your purchase, connect your HSA/FSA via the confirmation page or subscription portal.
Submit for reimbursement
Connect your HSA/FSA one time and submit your subscription purchase(s) for reimbursement.
How to Use
Use: On clean skin, apply 1-2 pumps morning and/or evening. Spritz any Osmosis Activating Mist and gently massage into skin. Follow with additional serum(s) and moisturizer if needed.
Pro Tip: Retinaldehyde is sun-safe so you can use in your morning routine as well!
Ingredients
Water, Glycerin, Phosphatidylcholine, Pentylene Glycol, Asiaticoside, Epilobium Angustifolium Flower/Leaf/Stem Extract, Hippophae Rhamnoides Extract, Chlorella Vulgaris Extract, Palmitoyl Tripeptide-38, Chrysanthemum Parthenium (Feverfew) Extract, Niacinamide, Dimethyl Sulfone, Lactic Acid, Panthenol, Pyridoxine HCl, Fulvic Acid, Prunus Serotina (Wild Cherry) Bark Extract, Retinal, Hydroxyproline, Beta-Glucan, Rubus Chamaemorus Seed Oil, Cinnamomum Camphora (Camphor) Bark Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Rosa Damascena Flower Oil, Lonicera Caprifolium (Honeysuckle) Flower Extract, Lonicera Japonica (Honeysuckle) Flower Extract, Hydroxypropyl Cyclodextrin, Cyclodextrin, Alcohol, Xanthan Gum, Sodium Hydroxide, Benzyl Alcohol, Potassium Sorbate.
Color may change or vary naturally over time. This does not reduce the efficacy of the product. This ingredient list is subject to change; please refer to product packaging for the most up-to-date ingredient list. Chirally correct ingredients used where possible.
Wonderful product especially as part of regime. Skin is looking so much better!! Thank you!
Love the product and ordering directly from Osmosis was easy. The product was delivered very quickly so very happy all around!
Thank you for your positive feedback! We are thrilled to hear that you love our product and had a smooth ordering experience with us. Our team works hard to ensure fast delivery to our customers. We truly appreciate your support and hope to continue providing you with exceptional service. Thank you for choosing Osmosis!
Great product but the packaging needs attention. I have used Osmosis products for a few years and for the last year or so, every lid cracks within weeks of purchase.
Hi!
Thank you for your feedback on the Calm serum. We're glad to hear that you've been enjoying it, but we apologize for the issue with the packaging. We take quality control very seriously and we're sorry that you've experienced this inconvenience.
In order to address this issue, we'd like to encourage you to reach out to our customer support team. They'll be happy to assist you and find a solution. We value your loyalty and we want to make sure you can continue to use our products without any problems. Thank you again for bringing this to our attention. We appreciate your support and we look forward to resolving this for you.
I guess this is a question more than a review, just curious if I can still use this product safely while pregnant?
Hi! Thanks so much for your review and your question about Calm and pregnancy. We are glad you are enjoying it.
It's always best to be cautious when pregnant. That said, the good news is that Calm contains a gentle form of Vitamin A called retinaldehyde and the amount in Calm is well below any safety concerns for pregnancy or breastfeeding. You can see more information on our Frequently Asked Question page. Of course, it is always a great idea to check with your doctor before starting any new supplements or products during pregnancy. They can give you the personalized advice that's best for you and your specific situation.
In the meantime, we are happy to answer any other questions you might have about Calm or other products we offer. Enjoy the rest of your pregnancy!
Truly calms sensitive skin around the eye and refreshes and soothes tired areas
Thank you for leaving a review for Calm. We are delighted to hear that it has worked well for you. We appreciate your feedback. Have a great day!
So far, so good. My skin is sensitive, and this product has been calming to my rosasia and my skin looks brighter and clearer.
Thank you for sharing your experience with Calm! We're thrilled to hear your feedback. We're here to support you on your skincare journey, and we can't wait to continue exceeding your expectations. Here's to calm, radiant skin! Thank you for choosing Osmosis!
I got a facial at a spa near me and the aesthetician recommended this product, and I have seen a noticeable change in my facial skin quality for the better. I recommend this serum.

Choose options







Pay with FSA & HSA.
Here’s how to use your HSA/FSA funds.
Checkout as guest
Select Gale at Checkout
Complete a health assessment
Pay with HSA/FSA or credit card
Pay with credit or debit card
Subscribe with your regular debit or credit card – do not pay with an HSA/FSA card.
Connect your HSA/FSA
After your purchase, connect your HSA/FSA via the confirmation page or subscription portal.
Submit for reimbursement
Connect your HSA/FSA one time and submit your subscription purchase(s) for reimbursement.
Wonderful product especially as part of regime. Skin is looking so much better!! Thank you!
Love the product and ordering directly from Osmosis was easy. The product was delivered very quickly so very happy all around!
Thank you for your positive feedback! We are thrilled to hear that you love our product and had a smooth ordering experience with us. Our team works hard to ensure fast delivery to our customers. We truly appreciate your support and hope to continue providing you with exceptional service. Thank you for choosing Osmosis!
Great product but the packaging needs attention. I have used Osmosis products for a few years and for the last year or so, every lid cracks within weeks of purchase.
Hi!
Thank you for your feedback on the Calm serum. We're glad to hear that you've been enjoying it, but we apologize for the issue with the packaging. We take quality control very seriously and we're sorry that you've experienced this inconvenience.
In order to address this issue, we'd like to encourage you to reach out to our customer support team. They'll be happy to assist you and find a solution. We value your loyalty and we want to make sure you can continue to use our products without any problems. Thank you again for bringing this to our attention. We appreciate your support and we look forward to resolving this for you.
I guess this is a question more than a review, just curious if I can still use this product safely while pregnant?
Hi! Thanks so much for your review and your question about Calm and pregnancy. We are glad you are enjoying it.
It's always best to be cautious when pregnant. That said, the good news is that Calm contains a gentle form of Vitamin A called retinaldehyde and the amount in Calm is well below any safety concerns for pregnancy or breastfeeding. You can see more information on our Frequently Asked Question page. Of course, it is always a great idea to check with your doctor before starting any new supplements or products during pregnancy. They can give you the personalized advice that's best for you and your specific situation.
In the meantime, we are happy to answer any other questions you might have about Calm or other products we offer. Enjoy the rest of your pregnancy!
Truly calms sensitive skin around the eye and refreshes and soothes tired areas
Thank you for leaving a review for Calm. We are delighted to hear that it has worked well for you. We appreciate your feedback. Have a great day!
So far, so good. My skin is sensitive, and this product has been calming to my rosasia and my skin looks brighter and clearer.
Thank you for sharing your experience with Calm! We're thrilled to hear your feedback. We're here to support you on your skincare journey, and we can't wait to continue exceeding your expectations. Here's to calm, radiant skin! Thank you for choosing Osmosis!
I got a facial at a spa near me and the aesthetician recommended this product, and I have seen a noticeable change in my facial skin quality for the better. I recommend this serum.



